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KGA-2727 is a potent, selective, high-affinity inhibitor of sodium glucose cotransporter 1 (SGLT1) with Ki of 97.4 nM and 43.5 nM for human SGLT1 and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 exhibits antidiabetic efficacy in rodent models.
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JANEX-1 (WHI-P131) is a small molecule inhibitor of JAK3 that selectively inhibits JAK3 at an IC50 of 78 µM without altering the activity of JAK1 or JAK2, or any other protein tyrosine kinases (IC50 ≥ 350 µM). E3535. Japanese ardisia Extract. E3862. Japanese Xylosma Twig Extract. E3486. Jasmine flower Extract.
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Sulfadimethoxine (Sulfadimethoxydiazine) is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections. Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
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Selleckchem.com - Bioactive Compounds Expert (Bioactive Compounds,Compound Libraries) Selleck products have been cited in over 60,000 studies Selleck Compound Libraries have been cited in over 2,000 studies Bioactive Compounds and Compound Libraries for COVID-19 Research
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Selleck Chemicals Blog-Visfatin attenuates the ox-LDL-induced senescence of endothelial progenitor cells by upregulating SIRT1 expression through the PI3K/Akt/ERK …
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Selleck Chemicals has established long-term and stable relationships with more than 10,000 customers from pharmaceutical and biotech companies to universities and research institutions. We …
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About. Selleck Chemicals LLC provides comprehensive and ongoing Inhibitors and modulators for multiple cell signaling pathways including MAPK, …
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